Megan Schröder


Early Stage Researcher


Raum: 5 G 02 366
Telefon: +4915229209270

Project Title

Optimization of Eligibility Criteria and Enrichment Strategies of Heart Failure Trials: Deep-dive Into Sex Differences and NT-proBNP Values with Trial and Registry data

Research Interest

Main research interest lies in the phenotyping and coding of heart failure (HF) using real-world data. Due to a wealth of new clinical trials and improved sub phenotyping, HF is now preventable and treatable for many patients. Therapy recommendations are continually improved as real-world evidence studies better capture and characterize HF patients, although there are still several limitations in the coding of heart failure. The focus of my PhD studies involves understanding the effect of sex differences in the outcome of HF patients, as well as identifying relevant sex differences in clinical trials that affect real-world representation. Improving clinical trials continues to be a focus of the pharmaceutical industry and improving enrichment strategies is one aspect of making clinical trials cheaper, quicker while maintaining scientific rigor. The second part of my PhD is focusing on the biomarker NT-proBNP, specifically in identifying the best cut-off for inclusion into HF clinical trials.



Prof. Dr. Christoph Gerlinger
Prof. Dr. Ulrich Mansmann
Prof. Dr. Eva Hoster

Curriculum Vitae


10/2021 – present: Ph.D. candidate Medical Research in Epidemiology and Public Health
10/2017 – 10/2019: Master of Science in Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany
03/2018: Clinical and Genetic Epidemiology Winter School, Ludwig-Maximilians-Universität München, Munich, Germany
10/2016 – 07/2017: Master of Art in Physical Activity and Health, Friedrich–Alexander University Erlangen–Nürnberg, Erlangen, Germany
08/2011 – 12/2015: Bachelor of Science in Kinesiology, Auburn University, Auburn, USA


02/2022 – current: Epidemiologist, Boehringer Ingelheim, Ingelheim, Germany
01/2020 – 01/2022: IMI Research Scientist, Bayer AG, Berlin, Germany
04/2018 – 04/2019: Research Internship and Master’s Thesis, Helmholtz Zentrum, Munich, Germany
11/2015 – 05/2016: Cardiac Rehabilitation Internship, East Alabama Medical Center, Opelika, USA


Zaghlool, S.B., Sharma, S., Molnar, M. et al. Revealing the role of the human blood plasma proteome in obesity using genetic drivers. Nat Commun 12, 1279 (2021). https://doi.org/10.1038/s41467-021-21542-4

Beyer K, Moris L, Lardas M The PIONEER Consortium, et al. Diagnostic and prognostic factors in patients with prostate cancer: a systematic review protocolBMJ Open 2021;11:e040531. doi: 10.1136/bmjopen-2020-040531

Lim YMF, Molnar M, Vaartjes I, Savarese G, Eijkemans MJC, Uijl A, Vradi E, Suzart-Woischnik K, Brugts JJ, Brunner-La Rocca HP, Blanc-Guillemaud V, Couvelard F, Baudier C, Dyszynski T, Waechter S, Lund LH, Hoes AW, Tyl B, Asselbergs FW, Gerlinger C, Grobbee DE, Cronin M, Koudstaal S. Generalisability of Randomised Controlled Trials in Heart Failure with Reduced Ejection Fraction. Eur Heart J Qual Care Clin Outcomes. 2021 Oct 1:qcab070. doi: 10.1093/ehjqcco/qcab070. Epub ahead of print. PMID: 34596659.